Narcolepsy – Essential to know the Facts

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NarcolepsyEvery living thing needs rest at some point. Sleep is very essential and one of the important functions of the human physiology. It is important which makes a person to recover from the previous tiredness and it also helps them to involve actively in the work, task or any event. However, there is one in 2000 people who get roughly affected by the disease called narcolepsy. Narcolepsy is a sleeping disorder in which the sleeping and waking cycle of the person generally leading to the daytime sleepiness, involuntary sleeping issues, hallucinations and sleeps paralysis. Hypocretin is an important chemical that is present in the brain which is responsible for regulating wakefulness.

The first discovery of Narcolepsy has come in the late 19th century, however, in the 20th century, it has gained more interest and many studies has been done on this disorder. It was found the issue is caused by the lateral hypothalamus. The Orexin producing neurons in the lateral hypothalamus has been reduced in number and thus resulted in the symptoms of narcolepsy in a person. The problem requires an effective treatment eventually lead to the discovery of nootropic drug called Modafinil.

The main role of the treatment is to reduce the daytime sleepiness and other issues associated with this sleep disorder and also to improve the tone in the muscles. However, not everyone will be able to experience both properties as they are classified and treated differently. Modafinil is the first medication that is evolved to treat this sleeping disorder and other symptoms regarding sleep and Sodium Oxybate for cataplexy.

The discovery of Modafinil has replaced the use of other central nervous system stimulants which has been practicing for years. It is because of superior efficacy, better control, and lesser side effects when compared to Amphetamines, Methylphenidate, Mazindol, Selegiline, and Pemoline. In the following, we will compare the effect of Modafinil with the other alternative medications that are used for treating narcolepsy. You will also be able to buy Modafinil online easily.

Amphetamines are the oldest medications that are used in the treatment of narcolepsy since the 1930s. amphetamine increases the quantity of neurohormones dopamine and nor-adrenaline whereas the use of Modafinil medications helps to increase the serotonin and Glutamate also. The both of the drugs would act on the areas of the thalamus and the hippocampus, additionally, Modafinil acts on the amygdala. As they are old, the amphetamines do cause some side effects since the medications get to acts on the different areas of the brain. The side effects that are caused by the intake of amphetamines include irritability, headache, nervousness, palpitations, insomnia, nausea, and psychosis. Using these drugs for a long period of time would lead to tolerance issue for which the body gets adapted. Also, it is recorded that person who takes an overdose of the medication has become the addiction to the drug specifically with the effect of methamphetamine present in the system. However, taking Modafinil medication, on the other hand, was more specific in terms of treating narcolepsy which helps in promoting wakefulness in the body and also has only lesser side effects and it will not develop any tolerance to a person.

To know more about the uses and properties of Modafinil, the structure of the medication is unique, neurochemicals profile and the behavioral effects of the drugs include both norepinephrine and dopamine transporters which help in increasing the concentration. Modafinil also helps in increasing the serotonin and Glutamate in the brain, however, it decreases the GABA levels. It is achieved by elevating the histamine levels in the hypothalamus. The intake of Modafinil affects the dopamine in the striatum, and nucleus accumbens, norepinephrine in the hypothalamus, and ventrolateral preoptic nucleus and serotonin in the amygdala and prefrontal cortex.

The excretion is done by the liver and the kidney, as the drug will be metabolized in the liver. The mild and the common side effects that are caused by the intake of the medication does include a headache, nausea, anxiety, and insomnia. However, these side effects are reported in 10% of the patients who are taking Modafinil. By this, it is clear that there is a 90% chance for good quality of life while taking Modafinil for treating narcolepsy. You can also buy Modafinil online now for immediate use.

Not only Modafinil is used for creating wakefulness, it is also used as a cognitive enhancer. It is considered a breakthrough drug and also has a vast biochemical action profile and it can also be used for many other purposes. The use of Modafinil has resulted in the improvement for kids who are suffering from the ADHD. Modafinil is also effective in patients who are dealing with,

  1. Negative psychosomatic symptoms
  2. Depersonalization disorder
  3. Seasonal affective disorder

There are also some other conditions where the use of Modafinil has improved the quality of life and performance of an individual includes:

  • Resistant depression and other types;
  • Fatigue due to systemic illness;
  • Sleep apnea;
  • Fatigue syndromes;
  • Schizophrenia;
  • Bipolar disorder;
  • Delayed sleep phase syndrome;
  • Parkinson disease;
  • Weight loss;
  • Beneficial in opioid and cocaine addiction;
  • Motion sickness;
  • Cognitive enhancer;
  • Used by armies.

In the modern world, everything has became very easier thus a person can buy Modafinil online. There are thousands of people who are getting very much benefited by the use of Modafinil and it also helps them to lead their life.

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