WHAT IS Norvasc/Amlodipine?

• Norvasc/Amlodipine is in a class of drugs called Phoslo/calcium channel blockers. Norvasc/Amlodipine relaxes (widens) the blood vessels (veins and arteries), making it easier for the heart to pump and reducing its workload.
• Norvasc/Amlodipine is used to treat hypertension (high blood pressure) and to treat angina (chest pain).
• Norvasc/Amlodipine may also be used for purposes other than those listed in this medication guide.

WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT Norvasc/Amlodipine?

• Do not stop taking Norvasc/amlodipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse.

WHAT HAPPENS IF I OVERDOSE?

• Symptoms of an Norvasc/amlodipine overdose include dizziness, weakness, chest pain, shortness of breath, fainting, unusually fast or slow heartbeat, coma, slurred speech, and confusion.
• Seek emergency medical attention.

WHAT DRUG(S) MAY INTERACT WITH Norvasc/Amlodipine?

• medicines for seizures (Carbatrol/carbamazepine, phenobarbital, Dilantin/phenytoin, Mysoline/primidone, zonisamide)
• medicines for fungal infections (Diflucan/fluconazole, Sporanox/itraconazole, Nizoral/ketoconazole, voriconazole)
• antiinflammatory drugs (NSAIDs, such as Motrin/ibuprofen)
• herbal or dietary supplements such as ginger, gingko biloba, ginseng, hawthorn, ma huang (ephedra), melatonin, St. John's wort, went yeast
• water pills (diuretics)
• barbiturates such as phenobarbital
• medicines for prostate problems
• zileuton
• imatinib, STI-571
• local anesthetics or general anesthetics
• some medicines for depression or mental problems (Sarafem/fluoxetine, Luvox/fluvoxamine, nefazodone)
• zafirlukast
• grapefruit juice
• bosentan
• medicines for HIV infection or AIDS
• medicines for high blood pressure
• yohimbine
• some medicines for heart-rhythm problems (Pacerone/amiodarone, Dilacor/Diltiazem cr/diltiazem , Calan sr/verapamil)
• rifampin, rifapentine, or rifabutin
• some antibiotics (Biaxin/clarithromycin, Eryc/erythromycin, telithromycin, troleandomycin)

WHAT HAPPENS IF I MISS A DOSE?

• Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

WHAT SHOULD I DISCUSS WITH MY DOCTOR BEFORE TAKING Norvasc/Amlodipine?

• If you are over 65 years of age, you may be more likely to experience side effects from Norvasc/amlodipine. Your doctor may prescribe a lower dose of this medication.
• Before taking Norvasc/amlodipine, tell your doctor if you have
  • liver disease; or
  • another disease of the heart or blood vessels such as sick sinus syndrome, aortic stenosis, heart failure, low blood pressure, or coronary artery disease.
• It is not known whether Norvasc/amlodipine passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.
• You may not be able to take Norvasc/amlodipine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Norvasc/Amlodipine is in the FDA pregnancy category C. This means that it is not known whether Norvasc/amlodipine will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

HOW SHOULD I TAKE Norvasc/Amlodipine?

• Do not stop taking Norvasc/amlodipine without first talking to your doctor, even if you begin to feel better. If you stop taking the medication, your condition could become worse.
• Store Norvasc/amlodipine at room temperature away from moisture and heat.
• Take Norvasc/amlodipine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.

WHAT ARE THE POSSIBLE SIDE EFFECTS OF Norvasc/Amlodipine?

• Other, less serious side effects may be more likely to occur. Continue to take Norvasc/amlodipine and talk to your doctor if you experience
  • nausea, diarrhea, or constipation; or
  • headache;
  • insomnia;
  • flushing;
  • fatigue or tiredness;
  • increased or difficult urination.
  • abdominal pain;
  • vivid or abnormal dreams;
• If you experience any of the following serious side effects, stop taking Norvasc/amlodipine and contact your doctor immediately or seek emergency medical treatment:
  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • chest pain;
  • psychosis;
  • unusually fast or slow heartbeat;
  • jaundice (yellowing of the skin or eyes); or
  • severe dizziness or fainting;
  • swelling of the legs or ankles.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

WHAT SHOULD I AVOID WHILE TAKING Norvasc/Amlodipine?

• Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness or dizziness while taking Norvasc/amlodipine.
• Use caution when you stand or sit up from a lying position, especially if you wake up during the night. You may become dizzy when changing positions.
• Follow any recommendations your doctor makes about diet or exercise.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.